TY - JOUR AU - Gamboa, Maryelle Moreira Lima AU - Gregianin, Lauro PY - 2013/07/23 Y2 - 2024/03/29 TI - Writing a research protocol in pediatric oncology JF - Clinical and Biomedical Research JA - Clin Biomed Res VL - 33 IS - 2 SE - Seção de Bioética DO - UR - https://seer.ufrgs.br/index.php/hcpa/article/view/35786 SP - AB - <span style="mso-ansi-language: EN-US;" lang="EN-US"><span style="font-size: small;"><span style="font-family: Times New Roman;">Children are considered an especially vulnerable population in a clinical trial. Specific regulations of research in pediatrics are focused upon protection from potential risks. Clinical trials in oncology <span style="color: black;">have become an important step to the researchers to discover new drugs, new combinations of known drugs and new methodologies.</span> The aim of this manuscript is to help the starter researchers to elaborate pediatrics oncology protocols for clinical trials. This guide describes the relevant aspects before writing a research protocol and a template of research protocol. Moreover, it shows the importance of a well-designed research protocol and its attachments - informed consent and assent forms – in a pediatric oncology study.</span></span></span> ER -