Diagnosis, risk factors and pathogenesis of preeclampsia

Authors

  • Rafael Bueno Orcy Programa de Pós-Graduação em Ciências Biológicas: Fisiologia, Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, HCPA
  • Renata Pedrini Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, Hospital de Clínicas de Porto Alegre
  • Pedro Piccinini Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, Hospital de Clínicas de Porto Alegre
  • Sabrina Schroeder Serviço de Ginecologia e Obstetrícia, Hospital de Clínicas de Porto Alegre
  • Sérgio Hofmeister Martins-Costa Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
  • José Geraldo Lopes Ramos Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
  • Edison Capp HCPA/UFRGS, Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, Hospital de Clínicas de Porto Alegre
  • Helena von Eye Corleta Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, Hospital de Clínicas de Porto Alegre

Keywords:

pré-eclâmpsia, diagnóstico, fatores de risco, fisiopatologia, resistência à insulina

Abstract

Preeclampsia is an illness of the gestation that involves fetal growth restriction, prematurity and, in more severe cases, death of mother and fetus. It is characterized by maternal hypertension, significant proteinuria (? 0,3g/24 h), edema, vasoconstriction of maternal blood vessels and consequent increase in vascular resistance. Many studies discuss risk factors, pathogenesis and diagnostic criteria of preeclampsia; however, there are large variations in presentation and clinical course of this illness, which make interpretation of fre-quently conflicting results difficult. Diagnostic standardization and research of genetic and molecular bases can bring a better understand-ing of this pathology in a near future. In this paper, we present a review of the literature, stressing the relation between preeclampsia and insulin resistance.

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Published

2008-01-02

How to Cite

1.
Orcy RB, Pedrini R, Piccinini P, Schroeder S, Martins-Costa SH, Ramos JGL, Capp E, Corleta H von E. Diagnosis, risk factors and pathogenesis of preeclampsia. Clin Biomed Res [Internet]. 2008Jan.2 [cited 2022May29];27(3). Available from: https://www.seer.ufrgs.br/index.php/hcpa/article/view/1981

Issue

Vol. 27 No. 3 (2007): Revista HCPA

Section

Review Articles

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